Biomarker Signature May Predict Aggressive Disease in African American Men With Prostate Cancer


When Tumor is the Rumor and Cancer is the Answer

Biomarker Signature May Predict Aggressive Disease in African American Men With Prostate Cancer

By Matthew Stenger

PROSTATE CANER JUST DOES NOT SEEM TO BE HE SAME ANIMAL IN AFRICAN AMERICAN  MEN EVEN AFTER CORRECTING FOR SOICECONOMIC STAUS. ACCESS TO CARE, CULTURAL MORES ( WHICH  ALL HAVE A ROLE) THIS STUDY SUGGEST THAT THERE IS A MARKER, A BIOMARKER UNIQUE TO BAD PROGNOSIS PROSTATE CANCER IN BLACK MEN. THE STATISTICS AND TERMS ARE FAIRLY HEAVY BUT THE TAKE HOME IS THAT THERE MAY BE MARKERS IN THE PROSTATE TISSUE THAT IDENTIFY O WILL DO POORLY . FURTHER STUDY IS CRUCIAL AS TO WHAT TO DO WITH THIS INFORMATION IF IT IS CORROBORATED  DR RYAN

Key Points:

  • Dysregulation of AMACR, ERG, FOXP1, and GSTP1 and loss-of-function mutations for tumor suppressors NKX3-1 and RB1 were associated with a significantly increased risk of pathologic T3 disease in African American men.
  • Dysregulation…

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